UPDATE JUNE 30TH, 2016 ;








“…planetary scientist Joseph Kirschvink has been trying to find a definitive answer to a hotly debated theory that suggests humans have an in-built magnetically guided ‘compass’ sense. The California Institute of Technology researcher acknowledges the topic of ‘magnetoreception’ is scientifically controversial...During the experiment, human test subjects were placed in specially designed, darkened space known as a Faraday cage, where they were then exposed to a cycle of magnetic fields similar to the Earth’s.

Through EEG testing, Kirschvink was able to witness repeated active brain responses to the presence of a magnetic field - a consistent reaction which up until now has reportedly eluded the scientific community.”






The key is something called an inversion layer, a region of the atmosphere where the air temperature increases with altitude instead of experiencing the usual decrease. Such layers can develop after calm, sunny days, says Laine. After sunset, warmer air rises while the surface cools, and continuing calm conditions mean the two temperature regions don't mix. According to Laine and his team, this inversion layer then acts like a lid, trapping negative electrical charge in the region below it and positive charge in the air above. When a geomagnetic storm hits Earth, the lid breaks and the charge is released, creating the weird sounds.





“…the brothers are paralyzed after the sun’s rays disappear, and are unable to move, eat, or talk again until the sun rises.









Types of Synchronicity


Predictive: This is where you see, think or do something that links to an outcome. The classic example is thinking of someone and them calling you.

Guiding: This is where all signs guide you to a specific outcome. This could be you thinking of giving up on your music career because of a lack of work and just as you are about to do so, you get a phone call from someone trying to book you for work.

Reflective: This is where you are forced to reflect due to a synchronistic event. An example would be if you decided to cancel your gym membership and then as you go to do it an email hits your inbox about the benefits of exercise, making you reflect on if you have made the right decision or not.

Testing: This is where synchronicity tests you ego. An example would be if you had a food addiction and absolutely loved fried chicken, when thinking about this addiction a fried chicken advert comes on the TV. Testing your ability to fight the temptation. Be strong, don’t do it!!!










We have virtually ZERO understanding of history

History requires students to understand causal relationships, and how things are correlated, and how things have influence way beyond their original occurrence. It requires you to understand logic, and ideologies like religion, philosophy and sociological movements - i.e., political beliefs and how technology changes human existence. It requires you to understand human beings, and their motives....college graduates know little of history, and thus have essentially nothing upon which to base their knowledge of current events, either.

























































BASIS FOR 432 ( hertz – music) found in Nature vs 440 Contemporary

Music Scale : One important artifact is the sky itself ;


For each degree of 360 the earth travels through, we have 12 relational points

corresponding to house divisions referenced.


So 360 * 12 = 4320


Where as 4400/360 = 12.2222


If we view "12" as a natural cycle limit, which it is, then 440 introduces noise

and inaccuracy into the system.


In short ones personal conscious reference of space time is distorted on a

fundamental level.


Global gravity modulation affecting mass and individual behaviour occurs in many



One important way is via regular pulses every four minutes, day and night.


432 vs 440 also plays an important part in this sequencing.




( One of my all time favourite articles! ) :




Psychokinetic Action of Young Chicks on the Path of An Illuminated Source

"in over 80 different experimental trials, a group of 15 baby chicks were ‘imprinted’ on a robot…

and were able to control it… by nothing more than their conscious intent!"


"In the presence of the chicks' intention, the robot's movements were no longer random; it

approached the cage of chicks two and a half times more often than it would approach an empty

cage (B).12 cage Robot's path with empty cage (A) cage Robot's path with with chicks

(B) Another possible explanation for distant healing comes from string theory.

String theory explains phenomena like electron tunneling. "Tunneling" is a misleading term,

since it implies that electrons travel through a tunnel. But in fact, they don't."

- Dawson Church











The chicks were looking through a pane of glass into a dark room, and all they could see was a

light, placed on top of the robot. This caused them to believe the light was their mother…

and they formed a very strong emotional desire for the light to come closer.


The robot had a random-number generator inside of it, which controlled the angle it would make

each time it turned. The turns came in regular, rapid intervals. Amazingly enough, within a very

short period of time, the chicks were able to get the robot to travel right in front of the window

— over 70 percent of the time, averaged out over the many different trials Dr. Peoc’h ran!


As you can see in this comparison photo from Dr. Claude Swanson’s seminal book The Synchronized

Universe, when the chicks could not SEE the robot (A), its behavior was completely random — and it

traveled all over the room. When the window was open, and the chicks could see the robot (B),

it goes back and forth, back and forth, right in front of the window, within no time.


Somehow, the powerful emotional intent of the chicks caused the robot to draw nearer to them.

Their strong emotional desire created a basic change in the way electricity was flowing through

the circuits in that computer chip, inside the robot! The result was that they were able to

continually control what numbers it was generating, so that it would stay near them.


This strongly suggests that energy as we now know it has a basic intelligence, and responds

to intent — particularly on a quantum level. This concept is totally foreign to mainstream

scientists, but that does not mean it is false. 


Dr Peter Fenwick, a well-known London neuropathologist, whereby chickens and rabbits

apparently influenced signals composed by a random-number generator for a robot close

to them, and human subjects apparently influenced the movements of the robot even though

its signals had been generated by a random-number computer program six months earlier.


Chicks hatched close to the robot imprinted on it as their mother and followed it about. It had

a random-number generator inside it controlling its movements, which checks showed were

truly random. The chicks were then removed and one placed so it could see the robot but

not follow it. Under these circumstances the robot spent measurably more time close to

the chick than away from it. The effect was that the chick was influencing the robot's



The generator was then removed to a computer away from the experimental area. The

same effect occurred. Non-imprinted chicks however had no apparent effect on the robot.


In the rabbit experiment, baby rabbits were frightened by the robot and kept away from it.

When the rabbits' movement was inhibited, the robot's movements became non-random

and it kept away from them. However, when one rabbit was starved and food was placed

on the robot, this behaviour was reversed and the robot brought the food to the rabbit.

It was found that humans likewise could influence the robot.












In an initial experiment (Peoc'h, 1986), we established that young chicks

aged from 1 to 7 days could attract towards them a robot controlled by a random

generator, and we subsequently developed this research further with the

use of a conceptually new machine, the Tychoscope 1, invented by P. Janin

(1977, 1988). (The name Tychoscope derives from the Greek "tukhe", which

means chance, and "skopein", which means to examine.)


He put a lighted candle on the top of the robot and put the chicks in the cage

where they could see it. Chicks prefer being in the light dur- ing the daytime,

and they "pulled" the robot toward them, so that they received more light.

Peoc'h also carried out experiments in which rabbits were put in a cage where

they could see the robot. At first they were frightened of it, and the robot

moved away from them; they repelled it. But rabbits exposed to the robot

daily for several weeks were no longer afraid of it and tended to pull it toward

them.' Thus the desire or fear of these animals influenced random events at

a distance so as to attract or repel the robot. This would obviously not be

possible if animals' desires and fears were confined inside their brains.

Instead, their intentions reached out to affect the behavior of this machine.

I interpret this influence in terms of a morphic field that projects out to the

focus of their attention, connecting them to it. Just as a field of intention

can affect people or animals at a distance, so it can affect a physical

system. In one case, intention has effects at a distance on the brain.

In the other case, intention has effects on random events in a machine.

As far as I know, no one has yet repeated Peoc'h's experiments.

It is possible that they involve some technical flaw that no one has yet

spot ted. But if they are reliable and repeatable, they are very important.






4 rue rks Genets, 44640 Saint Jean de Boiseclu, Frcince

Abstract - We tested the possible psychokinetic influence of 80 groups of


15 chicks on a randomly moving robot carrying a lighted candle in an otherwise

darkened room. In 7 1 % of the cases, the robot spent excessive time in

the vicinity of the chicks. In the absence of the chicks, the robot followed

random trajectories. The overall results were statistically significant at

p < 0.01.  Introduction For the past 25 years, researchers in parapsychology

have invented numerous devices driven by random sources to test the hypothesis

that consciousness

could alter their performance.


"Over eighty similar studies, in which a lighted candle was placed on a movable REG,

baby chicks kept in the dark, finding the light comforting, managed to influence the

robot to spend more time than normal in the vicinity of their cages.13 The largest

and most persuasive body of research has been amassed by William Braud, a

psychologist and the research director of the Mind Science Foundation in San

Antonio, Texas, and, later, the Institute of Transper-sonal Psychology."

- Lynne McTaggart,


"After that, the robot's experiments worked virtually 100 percent of the time.25

These anecdotal stories of the gremlin effect are not so far-fetched when you

consider the mountains of data generated by the PEAR laboratory, demonstrating

that human intention has the ability to make the random output of computers more

orderly even when the intention is not conscious or deliberate. Living consciousness

might have a major effect on microprocessor technology, which is now exquisitely

sensitive. The tiniest disturbances in a quantum process can be highly disruptive."

- Lynne McTaggart,


"In it, day-old chicks were put in the same room with a robot that had a picture of a

mother hen on it. The robot had been programmed to move randomly; however,

when the baby chicks looked at it, the randomness was disrupted. When observed

by the baby chicks, the robot's patterns of movement deviated toward the chicks

to a statistically significant degree. Apparently, as I suspected in my pre-adolescent

teens, chicks may rule the universe."

- Richard Bartlett













 He put a lighted candle on the top of the robot and put the chicks in the cage where

they could see it. Chicks prefer being in the light dur- ing the daytime, and they "pulled"

the robot toward them, so that they received more light. Peoc'h also carried out experiments

in which rabbits were put in a cage where they could see the robot. At first they were

frightened of it, and the robot moved away from them; they repelled it. But rabbits exposed

to the robot daily for several weeks were no longer afraid of it and tended to pull it toward

them.' Thus the desire or fear of these animals influenced random events at a distance so

as to attract or repel the robot. This would obviously not be possible if animals' desires and

fears were confined inside their brains. Instead, their intentions reached out to affect the

behavior of this machine. I interpret this influence in terms of a morphic field that projects

out to the focus of their attention, connecting them to it. Just as a field of intention can

affect people or animals at a distance, so it can affect a physical system. In one case,

intention has effects at a distance on the brain. In the other case, intention has effects

on random events in a machine.


Psychokinetic Action of Young Chicks on the Path of An Illuminated Source by René

Peoc’h. It was published in the Journal of Scientific Exploration, Volume 9, Number 2,

pp. 223-229, in 1995.














FASCINATING EXPERIMENT! The Frequency Glitch in the Matrix

This is really simple but has such an awesome effect. Fill a bucket full of water and place

it about 5 feet off the ground.


Place a subwoofer about 1 foot lower than the bucket. Run a plastic tube from the top

bucket down in front of the subwoofer. Tape the tube to the front of the speaker. Then

aim the end of the tube to an empty bucket on the floor. Get the water flowing from the

top bucket. Now just generate a 24 hz sine wave and set your camera to 24 fps and watch

the magic happen. Basically your cameras frame rate is synced up with the rate of the

vibrations of the water so it appears to be frozen or still. Now if you play a 23 hz sine

wave your frame rate will be off just a little compared to the sine wave causing the water

to "move backward" or so as it appears. You can play a 25 hz sine wave and cause the

water to move slowly foward.












Why Empaths Freeze Around Inauthentic People

Ever spent time with someone who on the surface seem as nice as pie but when with them you

feel awful and struggle to form a sentence? This is a caused by your Empathic antenna sensing

that all is not what it seems. You are detecting that what this person is showing is a fake persona

created to hide something from others.









































































































WIZARDRY 1,2,3 :
































Some of my influences;


In case its of interest the following have been huge influences on me and I offer this in case you feel it may be beneficial to you


I commented on these findings years ago in the videos on our you tube channel but  here is more info ;









Remote Biodynamic Sensing and the "Biogram"
by Michael Theroux




Language of the Stars



The most difficult obstacle to overcome concerning ICOMM lies with the exchange of information. Since conventional presumption is so anthropomorphically restrained, the academics insist on using our own cultural and societal development as a guide to choosing the proper cosmic linguistic form. Simple messages, binary call signals, pictograms, and even an artificial schematic language called Lincos have been suggested and even transmitted to the stars. But, even simple language can pose incredible difficulty for scholars wishing to make an interpretation. Earlier advanced cultures on our own planet have left us with innumerable writings which still evade academia's decryption. Even the late skeptic and mechanist Carl Sagan foresaw this conundrum: "European scholars spent more than a century in entirely erroneous attempts to decode Egyptian hieroglyphics before the discovery of the Rosetta Stone [1799] and the brilliant attack on its translation by Young and Champollion. Some ancient languages, such as the glyphs of Easter Island, the writings of the Mayas, and some varieties of Cretan script, remain completely undecoded at the present time . . . how can we expect that a civilisation vastly more advanced than we, and based on entirely different biological principles, could ever send a message we could understand?"

Dr. L. George Lawrence was clearly aware of these facts before he began his pioneering efforts in biodynamic ICOMM. Dr. Lawrence proposed that certain advanced civilisations would have developed a means of communication utilising purely biological principles. This biological exchange of information has been previously outlined in parts I and II of this article, which also detail Dr. Lawrence's experiments in biodynamic transfer of information. Dr. Lawrence stated that these galactic cultures may have communicated by a method now lost to our civilisation — eidetic communication — where the biodynamic energy transfer acts as the carrier, and the patternate content is the modulation. This patternate content is the actual [44] eidoform, or complete eidetic picture. What makes this method superior to conventional radio reception is the fact that biodynamic information is transmitted in a longitudinal point-to-point fashion. One doesn't have to wait light years for the reception of a message — it is nearly instantaneous. This may be likened to simple remote viewing, only in this case it is device assisted — ensuring minimal errors. Gerry Vassilatos has done substantial work in this field which he calls Device Assisted Remote Viewing — and with notable success.




Remote Biodynamic Sensing and the "Biogram"




Detecting Biodynamic Signals: Interstellar Communication


Our Videos ;


I've benefitted also from studying Kayser and Helholtz, here is a very good link ;


Also this site is quite good



Other influences :





Barbara Hero

John Ernest Worrel Keely

Just about everyone mentioned in 'The Secret Life of Plants'


Joel Sternheimer



The Little Prince

Peter Pan

Puss'n Boots

David Copperfield


God, or what ever you wish to call him, 'it'


The list is endless....


but the key came from a strange blue spark that popped in front of me one day,

I know that sounds, well, I know how that sounds..... but thats just the way it is, was.....


LANGUAGE OF THE STARS : Detecting Biodynamic Signals, Interstellar Communication
Earlier advanced cultures on our own planet have left us with innumerable writings which still evade academias decryption. Even the late skeptic and mechanist Carl Sagan foresaw this conundrum: śEuropean scholars spent more than a century in entirely erroneous attempts to decode Egyptian hieroglyphics before the discovery of the Rosetta Stone [1799] and the brilliant attack on its translation by Young and Champollion. Some ancient languages, such as the glyphs of Easter Island, the writings of the Mayas, and some varieties of Cretan script, remain completely undecoded at the present time ¦how can we expect that a civilization vastly more advanced than we, and based on entirely different biological principles, could ever send a message we could understand?

Dr. L. George Lawrence was clearly aware of these facts before he began his pioneering efforts in biodynamic ICOMM. Dr. Lawrence proposed that certain advanced civilisations would have developed a means of communication utilising purely biological principles. This biological exchange of information has been previously outlined, which also detail Dr. Lawrences experiments in biodynamic transfer of information. Dr. Lawrence stated that these galactic cultures may have communicated by a method now lost to our civilisation ” biological communication ” where the biodynamic energy transfer acts as the carrier, and the patternate content is the modulation. This patternate content is an actual eidoform, or complete eidetic picture. As an alternative to conventional radio reception, biodynamic information appears to be transmitted in a longitudinal point-to-point fashion. One wouldnt have to wait light years for the reception of a message ” it could be nearly instantaneous.
Determining the Method of Transmission

Dr. Lawrence was not without his own assumptions concerning the possible methods of galactic transmission. Of course, we have to begin somewhere, and Dr. Lawrence, being a radio engineer, followed the simple progression entailed in sending and receiving conventional radio communications. This follows the Russian theorist Y.I. Kuznetzovs outline of the communication process via the concepts of communication, coding, signal, and modulation. Lawrences version would be detailed thusly: The communication (Eidetic picture) would be converted into a form suitable for transmission (biodynamic signal), the coding being the method of conversion, and the modulation (patternate content) would be the change in the parameters of the emission serving as the carrier of the (biodynamic) signal. For reception, one would simply reverse this process.

Dr. Lawrence arrived at these conclusions based on his qualitative analysis of the sound emitted from his experimental setup. The modulations he heard displayed a character not unlike other conventional transmissions, which led him to work on their immediate conversion to visual images. At the very heart of Dr. Lawrences system was a unique form of biodynamic transducer which enabled him to receive and transmit signals of a biological origin.


Ether Physics

Biotechnology and Related Research

Electrical Theory

Informatics and Computer Science

Artificial Intelligence

Plant Research

Radio Science

Alternative Energy



Remote Biodynamic Sensing and the "Biogram"
Detecting Biodynamic Signals: Interstellar Communication


Remote Biodynamic Sensing and the "Biogram"




Detecting Biodynamic Signals: Interstellar Communication







Our Videos ;



Peter Lindemann -- Electric Motor Secrets





Resources for Cosmo-Bio Cycles Studies:

Stopping Seizures with 10 Hz generator

Cosmic Influences on Human Behavior, Michael Gauquelin (1985)
How Cosmic and Atmospheric Energies Influence Your Health, Michael Gauquelin (1991)
Cosmic Influences on Humans, Animals, and Plants, John T. Burns (He served as the Executive Director of the Foundation for the Study of Cycles for five years).
The Fields of Life: Our Links with the Universe by Dr. Harold Saxton Burr, 1973
Moon Rhythms in Naure: How Lunar Cycles Affect Living Organisms, Klaus-Peter Endres et al
The Lunar Effect: The Moons Effect On Our Weather, Harry Al*censored*; Moana Press (NZ) 1989.





”Interdisciplinary Cycles Research Institute (CRI)
Cycles Magazine and Journal is published four times a year.



Cycles in the Universe



Dennis Klocek, Astrological Weather Prediction



Richard Nolle explains effects like Supermoons



Eric Learner, Plasma Physics Model of the Universe



Geoff Haselhurst, cosmology-physics



Arcos Cielos Research Center (Eco, Science, Art etc¦)



Public Orgonomic Research Exchange

Cosmosophy: Cosmic Influences on the Human Being, Rudolf Steiner and A. R. Meuss

Cosmic Influences on Mind & IQ, S. S Chatterjee

Sun and Earth, Herbert Friedman; Scientific American Library, 1987

Tutankhamun Prophecies, Maurice Cotterell; Appendix 1: The Sun

Earthmind: Communicating With the Living World of Gaia, Paul Devereux, John Steele, and David Kubrin (1992)


Time on the Brain: How You Are Always Living In the Past, and Other Quirks of Perception

I suggest that it is much more useful to try to make a geometric model of consciousness, to take seriously the idea of a parallel continuum, and to say that the mind and the body are embedded in the dream and the dream is a higher-order spatial dimension. In sleep, one is released into the real world, of which the world of waking is only the surface in a very literal geometric sense. There is a plenum - recent experiments in quantum physics tend to back this up - a holographic plenum of information. All information is everywhere. Information that is not here is nowhere. Information stands outside of time in a kind of eternity - an eternity that does not have a temporal existence about which one may say, "It always existed." It does not have temporal duration of any sort. It is eternity. We are not primarily biological, with mind emerging as a kind of iridescence, a kind of epiphenomenon at the higher levels of organization of biology.


We are hyperspatial objects of some sort that cast a shadow into matter. The shadow in matter is our physical organism.

You Have a ‘GPS’ in Your Brain, Could It Help You Find Love? Your Lost Dog?
Dr. Beitman talks of the “psychesphere,” and Dr. Fox talks of the “empathosphere”—a layer of existence around us that we can’t perceive with the five senses, but which contains emotional information we may pick up on with yet-to-be-discovered sensory receptors.

"If we make this discovery or understand better the phenomenon, said Dr. Beitman, we may be able to make useful coincidences more common in our lives. Perhaps this GPS could often help us find lost children. Maybe it could help us find love, or the right job, or a helping hand in a time of need."

"..people are somehow able to map their location in relation to emotionally significant people or places. “Just how [this works] is our fun question,” he said. "

“consciousness space grid” or “a grid of experience.”

In his book “Margins of Reality,” he wonders about the physical existence of human consciousness and how it may be mapped. He also ponders, from the perspective of quantum physics, how consciousness may move toward a goal. “A person is described as a ‘close’ friend or ‘distant’ relative, as ‘deep’ in thought or ‘high’ as a kite; an idea may be ‘central,’ ‘remote,’ or ‘far out’; and we allow our minds to ‘wander’ over various conceptual ‘grounds,’ before taking a ‘position’ on an issue.”

These are qualitative descriptions. He wonders if its possible to develop quantitative spatial descriptions related to consciousness. He theorizes that human consciousness is in wave form and physically moves as such through the brain and beyond. He said further development of consciousness mechanics could form a “grid of experience, along which consciousness proceeds toward its goal by making discriminations or associations at each juncture, much as in a puzzle maze or in the games of ‘Twenty Questions’ or ‘Charades.’”

Grid cells are located in the hippocampus and may also be located in the anterior cingulate part of the brain, which plays an important role in human emotion, said Dr. Bernard Beitman, a Yale-educated psychiatrist currently working from the University of Virginia, after reading some of the prize-winning research. “This emotional aspect of grid cell mapping could make particular locations more highly charged in our brain-based maps. Like the maps used in GPS navigation, these maps could then help us find pathways to emotionally important people, things, and situations,”


"In this model, perception and cognition are mathematically described as a continuous trajectory through a high-dimensional mental space; the neural activation patterns flow back and forth to produce nonlinear, self-organized, emergent properties - like a biological organism."

"The degree of curvature of the trajectory shows how much the other object is competing for their interpretation; the curve shows continuous competition. They sort of partially heard the word both ways, and their resolution of the ambiguity was gradual rather than discrete; it's a dynamical system."


Are brains analog, or digital?
"Mind "should be thought of more as working the way biological organisms do: as a dynamic continuum, cascading through shades of grey."  "The outside world is analog in many respects, so brains have to reflect that. But efficient and modular processing elements are digital, so brains ought to take advantage of that too."

When the state of the system travels toward a frequently visited region of that space, the destination may constitute recognition of a particular word or a particular object; but on the way there, the majority of the mental trajectory is in intermediate regions of that space, revealing graded mixtures of mental states.


Are Your Emotions Contagious?
Ever noticed that you feel happy around happy people and sad around sad or depressed people? This is known as "emotional contagion" and is facilitated by an interconnected network of cells in the brain.

"...emotions can be contagious, you can potentially "catch" fear, anger or joy from people without realizing it. If you tend to be an emotional sponge, it's vital to know how to avoid taking on an individual's negative emotions or the free-floating kind in crowds. Another twist is that chronic anxiety, depression or stress can turn you into an emotional sponge by wearing down your defenses. Suddenly, you become hyper-attuned to others, especially those with similar pain. That's how empathy works; we zero in on hot-button issues that are unresolved in ourselves. Negative emotions can originate from several sources. What you're feeling may be your own; it may be someone else's; or it may be a combination. I'll explain how to tell the difference and strategically bolster positive emotions so you don't shoulder negativity that doesn't belong to you. This wasn't something I always knew how to do. Growing up, my girlfriends couldn't wait to hit the shopping
malls and go to parties, and the bigger the better -- but I didn't share their excitement. I always felt overwhelmed, exhausted around large groups of people, though I was clueless why. "What's the matter with you?" friends would say, shooting me the weirdest looks. All I knew was that crowded places and I just didn't mix. I'd go there feeling just fine but leave nervous, depressed or with some horrible new ache or pain. Unsuspectingly, I was a sponge, sensing the emotions of people around me.
With my patients, I've also seen how absorbing other people's emotions can trigger panic attacks, depression, food-, sex- and drug-binges, and a plethora of physical symptoms that defy traditional medical diagnosis"

Spontaneous Remission of Disease in Over 3,500 Cases – What’s Happening? - See more at: http://naturalsociety.com/spontaneous-remission-disease-35000-cases/#sthash.vGYOlNfU.dpuf
What if I told you that all manner of disease – from cancerous tumors the size of oranges to brain diseases, gastrointestinal disease, parasites, loss of sight, mental disorders, reproductive issues, muscular diseases and even viruses – could go away spontaneously?

You don’t have to take my word for it. The Institute of Noetic Sciences has a database of over 3,500 documented, verifiable cases of diseases, often life-threatening, that go away all on their own.
- See more at: http://naturalsociety.com/spontaneous-remission-disease-35000-cases/#sthash.vGYOlNfU.dpuf


Don't Let Bad Friends Drag You Down
Who you are is a function of whom you know. Your friends help shape your outlook, values, emotions and behaviors. Psychologists call this "social contagion," and it can work for or against you.









stress management    16,844

depression remedies    12,374
treatment depression    13,513
depression treatment    12,226

affluenza        1,417




The Affluenza Epidemic
"..a 40% decrease in empathy currently, when compared with 20 or 30 years ago. The conclusions were based on the results of the Davis Interpersonal Reactivity Index test, which looks at the ability to imagine another person’s perspective and feel what they are feeling. A narcissist has no use for those pesky emotions."
Despite, or perhaps even because of, a vast wealth gap in this country, the affluenza disease is spreading among all socio-economic groups. Through social media and reality television shows like Keeping Up With the Kardashians, we feel we can, and should, keep up with this conspicuous consumption at all cost. Kids of all demographics are raised to believe they deserve the latest and greatest must haves and luxury goods, be they iPhones for five-year olds, the latest X-Box for 10-year olds, or designer handbags for teenage girls, regardless of what families can afford.
The social and psychological consequences can be devastating. We are raising a generation of narcissistic consumers and losing our moral compass along the way. Why? Because the more valuable money and objects become to a person, the less valuable other people or emotions or finding inner happiness becomes.
"...a more detailed definition of affluenza can be found in the book Affluenza: The All-Consuming Epidemic, which describes it as “a painful, contagious, socially transmitted condition of overload, debt, anxiety and waste resulting from the dogged pursuit of more”.The term "affluenza" has also been used to refer to inability to understand the consequences of one's actions because of financial privilege, notably in the case of Ethan Couch.

James relates the stimulation of artificial needs to the rise in affluenza. To highlight the spread of affluenza in societies with varied levels of inequality, James interviewed people in several cities including Sydney, Singapore, Auckland, Moscow, Shanghai, Copenhagen and New York.
James also believes that higher rates of mental disorders are the consequence of excessive wealth-seeking in consumerist nations.[4] In a graph created from multiple data sources, James plots "Prevalence of any emotional distress" and "Income inequality," attempting to show that English-speaking nations have nearly twice as much emotional distress as mainland Europe and Japan: 21.6 percent vs 11.5 percent.[5] James defines affluenza as 'placing a high value on money, possessions, appearances (physical and social) and fame', and this becomes the rationale behind the increasing mental illness in English-speaking societies. He explains the greater incidence of affluenza as the result of 'selfish capitalism', the market liberal political governance found in English-speaking nations as compared to the less selfish capitalism pursued in mainland Europe. James asserts that societies can remove the negative consumerist effects by pursuing real needs over
perceived wants, and by defining themselves as having value independent of their material possessions.

“The simple term would be spoiled brat,” he said.
Miller told the judge that the boy’s father “does not have relationships, he takes hostages.” He said Couch’s mother was indulgent: “Her mantra was that if it feels good, do it.”
Prosecutor Richard Alpert argued in court that if the boy continues to be cushioned by his family’s wealth, another tragedy is inevitable.  The term was popularized in the late 1990s by Jessie O’Neill, the granddaughter of a past president of General Motors, when she wrote the book The Golden Ghetto: The Psychology of Affluence. It has since been used to describe a condition in which children — generally from richer families — have a sense of entitlement, are irresponsible, make excuses for poor behaviour, and sometimes dabble in drugs and alcohol, explained Dr. Gary Buffone, a Jacksonville, Fla., psychologist who does family wealth advising. Dr. Suniya Luthar, a psychologist who specializes in the costs of affluence in suburban communities, told The Associated Press that her research at Columbia University in New York has shown that 20 percent of upper middle-class adolescents believe their parents would help them get out of a sticky situation
at school, such as being caught for the third time on campus with a bottle of vodka. The judge’s sentence reinforces that belief.

“What is the likelihood if this was an African-American, inner-city kid that grew up in a violent neighbourhood to a single mother who is addicted to crack and he was caught two or three times … what is the likelihood that the judge would excuse his behaviour and let him off because of how he was raised?” Luthar asked.

“We are setting a double standard for the rich and poor,” she added, noting the message is “families that have money, you can drink and drive. This is a very, very dangerous thing we’re telling our children.”

Few psychologists would argue that being raised in an atmosphere of instant gratification and negligible consequences for bad behavior is healthy for child development. In addition, Couch’s risky behavior might indicate alcoholism and, if he truly were evidencing a pathological sense of entitlement or lack of empathy for others, it’s possible he might be diagnosable with a personality disorder. These are legitimate conditions, although they typically do not result in such a massive reduction in sentencing as was seen in this case. It is ironic that, in arguing Couch is a victim of bad parenting free of consequences for antisocial behavior, the defense and judge appear to have merely continued exactly this pattern, demanding unbelievably soft consequences for the death of four.

It is hard to escape the conclusion that money and privilege did indeed influence this case, but not through a psychological illness. Instead, the judge managed to convey the impression that the wealthy are able to buy a different justice from the poor.   Some news reports are comparing Couch’s outcome to that of a 14-year-old African American boy sentenced to 10 years juvenile detention by the same judge for one death resulting from a punch.  The cases aren’t identical, to be sure, but they convey an impression that wealth matters to the criminal justice system.

Ultimately, aside from Couch, the case has more losers than winners. The criminal justice system will suffer from the impression it is classist and unreliable. Psychology will take a hit for being linked to the affluenza term, despite it not being a product of psychological science. And the case will add to the unfair characterization of kids as spoiled, entitled brats, despite the fact that most youth are not. But the worst outcome, of course, is for the victims and their families who have been denied justice.



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  Scientists and doctors Robert Becker, John Ott, Walter Russell, Hans Nieper, M.D., Edward Russell, Abram Ber, Albert Einstein, William Tiller, Nikola Tesla, Edgar Cayce, Edward Bach, Gabriel Cousins, M.D., David Tansley, Marcel Vogel, Semyon and Valentina Kirlian, John Fetzer, Wilhem Reich, Christopher Hills, realise that the universe works electrically, among others.
"Living creatures consist of invisible electro-vibratory fields that not only form and develop what we recognize as our physical bodies, but also control the creation of new cells. These new cells replace those that are injured, worn out, or die from disease, impaired nerve impulse or environmental poisoning". Dr Cyril Smith, Nobel Prize winner in 1925 for cell electrical current research.

Soviet scientist, Dr. A.S. Presman (late 1960’s), discovered cells constantly communicate with each other through coded energy patterns. He studied a broad range of effects of the electromagnetic spectrum on living systems. He found that electromagnetic radiation can affect the spatial orientation of animals, modulate the rhythm of their physiological processes, and effect vital living processes adversely. He concluded electromagnetic fields serve as conveyers of information from the environment to the organism, within the organism, and among organisms. His data shows increases in the sensitivity to electromagnetic fields. The more complex the organism, the greater the sensitivity. Since man is the most complex, we are the most affected.
Georges Lakhovsky, 1925, stated, "the nucleus of a living cell may be compared to an electrical oscillating circuit. This nucleus consists of tubular filaments, chromosomes and mitochondria, made up of insulating material and filled with a conducting fluid containing all the mineral salts found in sea-water. These filaments are thus comparable to oscillating circuits endowed with capacity and self-inductance and therefore capable of oscillating according to a specific frequency." The Secret of Life, page 7.

Dr. Hans Jenny, 1972,was convinced that biological evolution was a result of vibrations, and that their nature determined the ultimate outcome. He speculated that every cell had its own frequency and that a number of cells with the same frequency created a new frequency which was in harmony with the original, which in its turn possibly formed an organ that also created a new frequency in harmony with the two preceding ones. Jenny was saying that the key to understanding how we can heal the body with the help of tones lies in our understanding of how different frequencies influence genes, cells and various structures in the body.

"This electrical system," says Nordenstrom (1980’s), "works to balance the activity of internal organs and in the case of injuries, represents the very foundation of the healing process." The electrical currents of the body are as critical to the well-being of the human body as the flow of blood. Disturbances in this electrical network may be involved in the development of cancer and other diseases.

Dr. Nancy Wertheimer (early 2000’s) Ph.D. epidemiologist who has been studying Electromagnetic Fields (EMF’s) for 20 years, has been looking at the epidemiological data in a different way — she is trying to associate EMF levels with health rather than disease. The level she is coming up with is a cut off of 1 milliGauss (mG). Russian researchers claim that 1/1000ths of a mG should be the standard.
The Bio-Electric Body believes that there are several stages of health between "optimum wellness", "degenerative disease" and "Cancer". Thus, we maintain our own living and sleeping quarters at 0.5mG and below.

Carlo Rubbia, (1984 Nobel Prize), "energy is superior to matter and determines its structure".

Cell researcher Bruce Lipton (current), PhD., "cells are 100 times more sensitive to electromagnetic information (signals) than to chemical information".

Dr. Valerie Hunt (1970’s on) has devoted the last 25 years to measuring and mapping human bio-energy. She is the first researcher to make objective, repeatable measurements of the full spectrum of the field surrounding the human body. Her most important readings occur in much higher vibrational ranges than those pertaining to muscle tension - with frequencies in the megahertz range and above. She reports that the energetic emanations of the body show anti-coherent changes before actual disease conditions can be diagnosed.

"The energy field starts it all". Dr. Burr (1940’s) discovered that all living things - from men to mice, from trees to seeds - are moulded and controlled by electro-dynamic fields, which could be measured and mapped with standard voltmeters. These "fields of life," or L-fields, are the basic blueprints of all life on this planet.

Nobel Prize winner Lehninger (1979) mentions in his textbook that some reactions in the living cell happen quite a lot faster than what corresponds to 37° temperature. The explanation seems to be that the body purposely directs chemical reactions by means of electromagnetic vibrations (biophotons).

Prof Fritze-Albert Popp (1975)proved that emission from the cells is not a result of DNA propagation, but the electromagnetic frequency directing the division of cells. Conclusive experimental evidence has been published to show that DNA is the source of these electromagnetic frequency and there is evidence to support the idea that electromagnetic frequency are responsible for triggering biochemical reactions in living cells.

Reba Goodman, Ph.D. Professor Emeritus Clinical Pathology; Special Lecturer in Pathology 2001.  The conventional stress-activated signal transduction pathways may not be the only mechanisms for extracellular signalling to the nucleus. Magnetic field-stimulated transcription in cell-free preparations implies that membrane interaction is not an essential element in transmitting the signal to the nucleus. Since magnetic fields penetrate cells and are not limited to interactions with the membrane there may be a direct effect of magnetic fields on DNA through interaction with conducting electrons in the stacked bases of the DNA. Electromagn Biol Med. 2008 ;27 (1):3-23 18327711 (P,S,E,B). Protein and DNA reactions stimulated by electromagnetic fields.

Martin Blank (1970’s on). Department of Physiology and Cellular Biophysics, Columbia University, New York, New York, USA. Studies with electric and magnetic fields in the extremely low-frequency range have shown that weak fields can cause charge movement. It appears likely that weak EMF can control and amplify biological processes through their effects on charge distribution.

Jacques Benveniste (1985), French immunologist, proposed that cells communicate via electromagnetic signals:
The Bio-Chemical Theory: "structural matching"
The Electromagnetic Theory: "electromagnetic signals"

Fig A The 3D structure of an antigen (or an agonist) matches the 3D structure of the antibody (or the receptor, respectively). This physical contact is what induces the cell function.
Fig B The agonist molecule carries and emits an EM signal which co-resonates with the receptors molecules, thus activating it, and inducing the cell function.

The "Electromagnetic Signals" Theory
Using various experimental protocols we are able to activate specific cell functions with the corresponding low frequency (<20 kHz) electromagnetic waves. This prompted us to hypothesize that the molecular signal is composed of such low frequency waves and that the ligand co-resonates with the receptor pretty much as the tuning of a radio device.
It is important to remark that these concepts do not violate any current biological or physical basic principle. It is well-documented that:
1) Molecules emit specific frequencies;
2) A complex set of high frequency waves can produce low frequencies according to the "beat frequency" phenomenon;
3) All biological interactions occur in water, since, on the average, there are ten thousand molecules of water per molecule of protein.

Quantum electro-dynamics calls for the existence of long range electromagnetic fields that can be transmitted by large - hundreds of angstroms - coherent domains present in water (adapted from E. Del Giudice & E. Preparata, 1994, Journal of Biological Physics, vol. 20, p. 105). Such long range EM fields would be capable of transmitting the EM message coming from molecules, thus generating a long distance specific attraction between two molecules with matching spectra, excluding non-resonating, unwanted random events. The field resulting from the aggregation of the two co-resonating molecules would obviously exhibit a different frequency which would then co-resonate with the next molecule or cluster of molecules which intervene in the next step of the biochemical reaction, and so forth and so on... The fact that small changes in the spectrum of a molecule (e.g. induced by a tiny structural change) would profoundly alter its resonating characteristics,
would explain how minute changes (e.g. phosphorylation, replacement of an ion by a similar one, switching of two peptides...) radically modify the molecular tertiary structure and function.
Proof positive - Homeopathy works, but dr jacques isn't around to hear his work vindicated
It is tragic that it has taken 16 years to vindicate the controversial discoveries of Dr Jacques Benveniste - and in the very week that he has died.
Dr Benveniste scientifically proved the basis of homeopathy in a series of experiments with water, which were published in Nature in 1988. Thereafter the medical establishment pilloried him, research funding was taken away, and his very promising career in science was ended. Television magician James Randi visited Benveniste's laboratories but, not surprisingly perhaps, was unable to verify his discovery.
But scientists, rather than celebrities, have finally proved his findings. Four independent laboratories, in Ireland, Italy, France and the Netherlands, have discovered that effects can occur below the level at which any molecule of the substance is present.
Sadly, their findings were published in the week that Dr Benveniste died following heart surgery.
(Source: Inflammation Research, 2004; 53: 181-8).
* The work of Dr Jacques Benveniste, and his struggle against the prevailing establishment, iss outlined in Lynne McTaggart's inspiring book The Field.

+"jacques benveniste" +"cell "

Fritz Albert Popp
The phenomenon of how information is transmitted within living systems was and is being extensively studied by a bio-physicist named Fritz Albert Popp. He discovered that photons provided the vehicle for which information was transmitted. Photons are light particles without mass. They transmit information within a cell and between cells. He showed that DNA of living cells stores and releases photons. He called this "biophotonic emission". The intensity is about 10 (18th) times lower than regular daylight. To study this phenomenon he developed an instrument called a photon multiplier which could detect the glow of a firefly 10 miles away. DNA uses a variety of frequencies as an information tool suggesting a feedback system of perfect communication through waves which encode and transfer information.
Another fascinating characteristic of photons is their coherence. In a healthy state the emission is more coherent than anything that man has ever developed. Quantum coherence means that subatomic particles are able to co-operate. These waves know about each other and are highly interlinked by bands of electromagnetic fields. They can communicate with each other. It is analogous to an orchestra where all photons are playing together but as individual instruments that are able to carry on playing individual parts. Therefore, biophotonic emission is a perfect communication system that transfers information to many cells across the body and to other bodies.
Another important characteristic of biophotons is that they follow biological rhythms (i.e., daily, weekly, monthly and annually). In healthy individuals the biophotons are extremely coherent and in rhythm with the world. In seriously ill people (i.e., cancer) they have lost their natural rhythm and coherence. The lines of communication were scrambled and they lost their connection with the world. In effect their light was going out.
Interestingly, Popp found in people with multiple sclerosis, that the opposite was true. They were in a state of too much order. They were taking in too much light, inhibiting the ability of the cells to do their job. Too much cooperative harmony prevented flexibility and individuality. In reality, they were drowning in their light.
In a stressed state, the rate of biophotonic emissions went up. This is a defense mechanism to try and return to homeostasis. Therefore biophotonic emission is a sort of correction mechanism in living systems.

Studying food, Popp found that the healthiest food has the lowest and most coherent intensity of light.
William Ross Adey
The final important principle looks at the actual intensity of the emission. William Ross Adey, while experimenting with cerebral cells in chicks, found they only responded to a certain frequency (10 Hz). Also, he found that the amplitude must lie within a specific (very low) range. This is called Adey’s window, and it is a limited range in which a biological system is able to respond to electromagnetic signals carrying information. Interestingly, this range falls within the same range in which Homeopathic signals are measured.
Popp found while studying Homeopathic remedies that they are an example of photon sucking. Homeopathic remedies are resonance absorbers. If a non-physiological frequency produces certain symptoms, a high dilution of a substance which could produce the same symptoms would still carry these oscillations. Like a tuning fork in resonance, a suitable homeopathic solution might attract and then absorb the non-physiological oscillations, allowing the body to return to normal.

Biophysical Controls Biochemistry

The implications of this statement are numerous and extremely important, not the least of which is that the biophysical level of an organism controls its biochemistry. For example, changing and adjusting the biochemistry of the human body can easily be accomplished with medications, supplements, diet, and even exercise, but this is only dealing with a disease state at a symptomatic level. However, affecting change at the biophysical level where cellular communication can be normalized will result in a balance of both the biophysical and biochemical levels. And how does one affect this type of change? Based on what we’ve learned from the research of Benveniste, Popp, and Adey, the answer is digital homeopathy.

Abstract FASEB Journal, 1999, vol. 13, p. A852
J. Benveniste, L. Kahhak, and D. Guillonnet. Digital Biology Laboratory, F-92140 Clamart.
Previous studies suggest that the electromagnetic molecular signal (EMS) can be digitally recorded and replayed [1-4]. We electronically captured, digitized, and transmitted the specific EMS of bacteria to a biological system sensitive to this EMS. First we digitally recorded EMS from E.coli K1, staphylococcus (3.5 million/ml) or saline. Latex particles, sensitized by a K1 antibody (ab), aggregate to E.coli K1 (kit, Pasteur Diagnostics). We then set up the ab-latex and E.coli antigen (ag) concentrations so as to obtain minimal aggregation. Next, we applied the E.coli or control recorded EMS for 2 min to ab-latex and ag which we subsequently mixed. After allowing the mixture to migrate for 13 min at 37°C in a capillary, we examined it under a microscope. A CCD camera generated 3 pictures that were analyzed using a dedicated software. E.coli K1 EMS induced the formation of larger aggregates than that of Staphylococcus or saline. The magnitude of
aggregation varied from day to day. Yet, by comparing E.coli data from controls of the same day, we seldom failed to detect E.coli in hundreds of experiments (mean of differences: 150 %). Thus, we are clearly able to identify a bacteria by playing its EMS signal. The latter is specific, since the effect of staphylococcus EMS on E.coli ag/ab reaction was close to that of saline. Since EMS travel a long distance in the form of a ".wav" file, it should become possible to detect any immunogenic substance from a remote location.
[1] Davenas et al., Eur. J. Pharmacol., 1987, 135:313; [2] Davenas et al., Nature, 1988, 333:816; [3] Aďssa et al., J. Immunol., 1993, 150:A146; [4] Benveniste et al., J. Allergy Clin. Immunol., 1997, 99:S175. Supported by DigiBio S.A.
Yolčne Thomas, Hedi Litime and ,Jacques Benveniste. CNRS URA 1442, 60206 Compičgne and Digital Biology, laboratory, 32 rue des Carnets, 92140 Clamart, France.
The molecular signal of PMA can be electronically transmitted and modulate neutrophil reactive oxygen metabolite (ROM) production as if PMA itself was added to the cells [1]. Experiments reported here were done blind or open at INSERM U 332, ICGM, Paris. Transmission was performed via an especially designed amplifier connected to two coils [2]. The source tube containing PMA (1 µM) or vehicle was placed on the input coil at RT, and target cells (1 million per ml) on the output coil ait 37° C in a humidified incubator. The amplifier was then turned on for 15 min transmission time and cells were then incubated for up to 45 min before measurement of cytochrome c reduction. Three or four amplifiers were used simultaneously for each experiment. An increase in ROM production was observed immediately after PMA transmission: (over vehicle transmission), 56.6 +- 15.5 %, mean +- SEM, and up to 60 min: 38.7 +- 14.8, n = 9. Peak PMA transmission effect varied
among individuals. Transmission of 4alpha-phorbol 12,13-dibutyrate, an inactive PMA analogue, did not stimulate neutrophil ROM production. The effect of PMA transmission was inhibited when 1) the amplifier was switched off: 42 ± 8 % vs -1.8 ±1.4 %, n = 6, and 2) the selective protein kinase C inhibitor GF109203X was added to the cells (8 µM) before PMA transmission.
These results, together with those previously reported, suggest that molecules emit signals than can be transferred to cells by artificial physical means in a manner that seems specific to the source molecules.
[1] Thomas et al., FASEB J. 1995, 9:A227; [2] Benveniste et al., FASEB J. 1994, 8: A398. Supported in part by Ministčre de l'Environnement, Bouygues SA, SAUR, and Association Science Innovante.
J. Benveniste, P. Jurgens and J. Aissa. INSERM U 200 and Digital Biology 'Laboratory, 32 rue des Carnets, 92140 Clamart, France.
Previous studies suggest that the biological activity of agonists can be transferred to water by electromagnetic means [1-7]. Since July 1995, in keeping with these results, we have digitized, recorded, and 'replayed' to water the activity of acetylcholine (ACh) or water (W) as control. ACh and W were recorded (16 bits, 22 KHz), for 1-5 sec, via an especially designed transducer, on the hard disk of a computer equipped with a Sound Blaster 16 card. Files were digitally amplified and the signal of digitally recorded ACh or W was replayed for 15 min, via the transducer, to 15 ml, W-containing plastic tubes. W thus exposed (dACh, dW), was then perfused to isolated guinea-pig hearts. In 13 open experiments, coronary flow variations were (%, mean +- SEM, nb of samples): W+dW(not stat. diff.), 3.3 +- 0.2, 20; dACh, 16.2 +- 1.0, 33, p = 4.1 e- 10 vs W+dW; ACh (0.1 µM), 23.4 +- 2.8, 12, P = 5 e-3 vs dACh. In 25 blind experiments: W+dW, 3.6 +- 0.3, 61; dACh,
20.4 +- 1.3, 58, p = 1 e- 16 vs W+dW; ACh (0.1 pM), 28.1 +- 2.3, 24, p = 3 e-3 vs dACh. Atropine inhibited the effects of both ACh and dACh. Moreover, we have recently transferred specific digital signals via telephone lines.
These results indicate that the molecular signal is composed of waveforms in the 0-22 Khz range. They open the way to purely digital procedures for the analysis, modification and transmission of molecular activity.
[1] Aissa et al., FASEB J. 1993, 7:A602; [2] Benveniste et al., FASEB J. 1994, 8: A398; [3] Aissa et al., J. Immunol. 1993, 150:Al46; [4] Aissa et al., FASEB J. 1995, 9:A425; [5] Citro et al., FASEB J. 1995, 9:A392; [6] Senekowitsch et al., FASEB J. 1995, 9:A392; [7] Thomas et al., FASEB J. 1995, 9:A227. Supported in part by Bouygues SA, SAUR, Dolisos, LSH and Association Science Innovante.
J. Allergy Clin. Immunol. 99:S175, 1997
J. Aďssa, P. Jurgens, W. Hsueh and J. Benveniste. Digital Biology Laboratory (DBL), 32 rue des Carnets, 92140 Clamart, France and NorthWestern University Medical School, Chicago, IL 60614, USA.
Ligands so dilute that no original molecule remained still retained biological activity which could be abolished by magnetic fields [1-3], suggesting the electromagnetic (EM) nature of the molecular signal. This was later confirmed by the electronic transfer to water (W) of molecular activity, either directly or after computer storage [4-7]. Here, we report its transfer via the telephone network. Ovalbumin (Ova) or W as control, was recorded (1 sec, 16 bits, 22 kHz) into a diskette in Chicago using a transducer and computer equipped with sound-card. Coded files were transferred to diskettes in DBL's computer as "attached documents" via Internet e-mail. After digital amplification they were replayed for 20 min via a transducer to 15 ml W-containing plastic tubes. Exposed W (dOva, dW), was then perfused to isolated hearts from Ova-immunized guinea-pigs. The heart operator was always blind while technical incidents revealed the identity of 4/19 files to the
computer operator. Coronary flow variations were (%, mean+SEM, nb of measures): naive W (negative control), 4.9+0.3, 41; dW, 4.4+0.3, 58; dOva, 24.0+1.4, 30, p= 4.5 e -17 vs dW; Ova (0.1 µM, positive control), 28.9+3.7,19, ns vs dOva. The hitherto neglected physical nature of the molecular signal emerges: EM radiation under 22 kHz that can be digitized, transferred long distances and replayed to W, which then mimicks the activity of the source-molecule. This implies novel strategies in chemistry, biology and medicine. [1] Davenas et al., Nature. 1988, 333:816; [2] Benveniste et al., CR Acad Sci Paris. 1991, 312:461; [3] Benveniste et al., FASEB J. 1992, 6:A1610; [4,5] Aissa et al., FASEB J. 1993, 150:A146 & 1995, 9:A425; [6] Thomas et al., FASEB J. 1996, [7] Benveniste et al., FASEB J. 1996, 10:A1479. Supported by Association Science Innovante.
J. Benveniste, J. Aďssa, P. Jurgens and W. Hsueh*
presented at Experimental Biology '98 (FASEB). San Francisco, April 20, 1998
For several years, we have activated various biological systems using the electromagnetic (EM) signal of the agonist molecule instead of the molecule itself. Signals are applied electronically, in real time, to target cells or organs. Alternatively, they are digitally recorded on a computer, either directly, using a purpose-designed transducer, or via the public switched network, and then replayed [1-9]. One of the main questions in this complex process of detection, recording, transfer and replay, is the integrity of the applied signal, which is a prerequisite for the specific expression of the molecular signal. We therefore investigated the specificity of digitized EM signals of acetylcholine (d-ACh) and histamine (d-H).

Materials and Methods
Heart preparation.
Isolated hearts from male Hartley guinea-pigs, ~= 300 g, were perfused according to the Langendorff method using Krebs-Henseleit buffer (pH 7.4) gassed with O2/CO2, 95/5 %, at a pressure of 40 cm H2O at 37°C.

ACh, or sodium acetate + choline chloride (AC) or H at 1µM, or water (W), were recorded (6 sec, 16 bits, 44 kHz) using a purpose- designed transducer and a computer equipped with a sound card.

d-ACh and d-H were applied to isolated guinea-pig hearts, perfused or not with the ACh inhibitor atropine or the H1 receptor blocker, mepyramine, both at 1 µM. d-W or d-AC, and ACh or H (1 µM), were also applied as negative and positive controls respectively. Coronary flow was then measured every min for 30 min and changes were calculated as % maximal coronary flow variation compared to three "time 0" values. Student's t-test for unpaired variates (Plot 40, Sigma Plot) was used to assess statistical significance.
Mechanical parameters (min. and max. tension, heart rate) were observed and recorded using dedicated software.
The effects on the maximal variation in coronary flow are shown in Table 1. ACh, H (1 µM), d-ACh, d-H induced highly significant changes, whereas d-W or d-AC were indistinguishable from spontaneous flow variations.
Atropine inhibited both the effects of ACh and d-ACh, but not those of H and d-H. Mepyramine inhibited the effect of both H and d-H but not those of d-ACh.

Variations in coronary flow following application of d-ACh and d-H were highly significant compared with controls, d-W and d-AC.
A typical effect of d-ACh on heart frequency and its inhibition by atropine are shown (figure 1).
[Vasodilation was induced in guinea-pig skin by d-ACh, whereas d-AC was ineffective (figure 2).]